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Guidance for Industry: Appendix B for Preparing a Claim of Categorical Exclusion or an Environmental Assessment for Submission to CFSAN

FinalHuman Foods Program05/01/2006

Description

Below are recommendations for the suggested format and types of information to submit to the agency in an environmental assessment.  An alternative approach may be used if the approach satisfies the requirements of the applicable statutes and regulations.

Key Topics

Terms and concepts identified from this document

Regulatory Context

Regulatory Activities

1
Food Additive Petition

Formal program for the review of animal food additives.

Document Types

2
Material Safety Data Sheets

Documents FDA does not intend to enforce submission for if unaltered

Environmental Assessment

Required documentation under 21 CFR 514.1(b)(14).; Document evaluating environmental impact of investigational IGAs; Document used to examine potential for environmental impacts.; Document evaluating environmental impact of the action; Document required to determine environmental impacts

Attributes

2
Expected Environmental Concentration

Calculated concentration of a substance organisms would be exposed to; Concentration of substance after dilution; Concentration organisms would be exposed to after considering fate parameters

Expected Introduction Concentration

EIC of the substance in wastewater effluents or sewage sludge; Concentration of substances introduced into the environment at the site of use

Technical Details

Substances

2
Food Additive

Substances intended for use in food that require premarket approval

Food Contact Substance

The FCS undergoes chemical or metabolic transformation; Components of the formulation already authorized for intended uses.

Testing Methods

1
Structure-Activity Relationships

SAR programs used to predict fate and effects when data is unavailable

Processes

1
Aerobic Biodegradation

Considered a rapid depletion mechanism if t½ is less than 8 hours.; Depletion mechanism identified in the sample data summary table.

Identified Hazards

Hazards

1
Adverse Environmental Impacts

Potential negative effects on the environment from a proposed action

Standards & References

External Standards

2
40 CFR 1508.27(b)(10)

Council on Environmental Quality definition of extraordinary circumstances

Endangered Species Act

Federal law protecting species and critical habitats

Related CFR Sections (2)

See Also (8)

Guidance for Industry: Appendix B for Preparing a Claim of Categorical Exclusion or an Environmental Assessment for Submission to CFSAN | Guideline Explorer | BioRegHub