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CPG Sec. 455.100 Inert Glandular Preparations *(OTC)*, Inadequate Full Disclosure and Claims

FinalCenter for Drug Evaluation and Research05/22/1987

Description

*When it was discovered that some glands produce hormones, a variety of glandular products were placed on the market for OTC medicinal use. Many of these commercial glandular preparations contained very little hormonal activity.

Key Topics

Terms and concepts identified from this document

Scope & Applicability

Product Classes

3
unapproved new drugs

Regulatory status of inert glandulars making false representations.

OTC drug

Nonprescription human drug products marketed without an approved application.

Inert Glandular Preparations

Glandular products with little hormonal activity intended for medicinal use.

Stakeholders

1
Dockets Management

Entity responsible for receiving written comments regarding the guidance

Regulatory Context

Document Types

1
Compliance Policy Guide

FDA regulatory reference documents (CPG 527.300, 555.300)

Technical Details

Substances

4
intrinsic factor

Exemption for stomach and duodenum preparations.

vitamin

Exemption for liver preparations limited to vitamin content.

desiccated whole or aqueous extracts

Form of animal glands subject to regulatory action.

hormones

Produced by glands; many preparations contain very little.

Related CFR Sections (2)

See Also (8)

CPG Sec. 455.100 Inert Glandular Preparations *(OTC)*, Inadequate Full Disclosure and Claims | Guideline Explorer | BioRegHub