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Mammography Quality Standards Act and Regulation Amendments: Small Entity Compliance Guide: Guidance for Industry and Food and Drug Administration Staff

FinalCenter for Devices and Radiological Health08/26/2024

Description

FDA has developed this Small Entity Compliance Guide (SECG) to explain the actions a small entity is required to take to comply with the MQSA rule and its implementing regulations. The March 2023 MQSA rule modernized mammography regulations and specifies that the mammography report given to patients specifies if the patient has dense or non dense breast tissue and includes a prescribed paragraph on the significance of breast density. The SECG also includes policy and recommendations previously found in the Policy Guidance Help System.

Scope & Applicability

Product Classes

5
Mammography

special purpose x-ray system

Digital Breast Tomosynthesis

supplement for mammography systems

Mobile units

subject to same standards as stationary facilities

Investigational Mammography Device

Devices used in studies under 21 CFR part 812

Computed Tomography of the Breast

Modality not regulated under MQSA

Stakeholders

10
mammography facility

hospital, outpatient department, clinic, radiology practice, mobile unit, office of a physician

industry representatives

members of the NMQAAC

consumer

members of the NMQAAC

practitioners

members of the NMQAAC

physicians

members of the NMQAAC

quality control technologist

responsible for maintaining monitoring data

supervisee

Individual performing tasks under direct supervision

inspector

person performing the annual MQSA inspection

audit interpreting physician

designated individual responsible for notifying IPs of audit results

referring healthcare provider

The provider to whom the mammography report must be sent.

Regulatory Context

Attributes

10
clinical image quality

standards for clinical image quality; Standard evaluated by accreditation bodies

direct supervision

Requirement for supervisor presence and observation

continuing education units

Measurement of ongoing training (CEU)

Board Certified

A qualification requirement for interpreting physicians.

recall rate

metric required in the medical outcomes audit

cancer detection rate

metric required in the medical outcomes audit

positive predictive value

metric required in the medical outcomes audit

Benign

A final assessment category for mammography findings.

Negative

A final assessment category for mammography findings.

breast density

One of the required overall assessments in the mammography report.

Identified Hazards

Hazards

2
Risk to human health

trigger for AMR

significant risk to human health

threshold for requiring patient notification

Related CFR Sections (7)

Related Warning Letters (5)

  • Bioresearch Monitoring Program/Institutional Review Board (IRB)

    United Health Products, Inc.

    2025-05-20
  • Bioresearch Monitoring Program/IRB

    Massachusetts Institute of Technology MIT

    2024-07-16
  • Investigational Review Board (IRB)

    Nobles Medical Technology II, Inc.

    2024-03-12
  • CGMP/QSR/Medical Devices/Adulterated

    Synovo Production, Inc.

    2023-04-04
  • Investigational Device Exemptions (Clinical Investigator)

    Kennedy, Philip R.

    2020-04-07

See Also (8)

Mammography Quality Standards Act and Regulation Amendments: Small Entity Compliance Guide: Guidance for Industry and Food and Drug Administration Staff | Guideline Explorer | BioRegHub