Description
This document is intended to provide guidance for “Animal Proteins Prohibited from use in Ruminant Feed,” 21 CFR 589.2000.
Scope & Applicability
Product Classes
2Animal food specifically for pets, handled by humans in the home; Specific animal food category mentioned regarding facility design; Specific animal food category where Salmonella contamination is considered adulteration.; Specific category including dog and cat food; Subject of various recalls and safety investigations.; Referenced in recalls and safety alerts; Industry segment adopting HACCP principles.; Specific animal food category including kibble and jerky treats; Includes dry pet food (ki
animal proteins prohibited from use in ruminant feed
Stakeholders
4Source of animal protein products that may certify compliance
entities involved in the distribution of devices
Includes manufacturers and mixers of complete and intermediate feeds; Entities subject to the regulation and potential exemptions
Firms that obtain processed animal protein from more than one source; Entities subject to the regulation and potential exemptions
Regulatory Context
Attributes
1Required marking on shipping containers for exported prohibited material
Identified Hazards
Hazards
1Mammalian protein that must not be fed to ruminants
Related CFR Sections (1)
Related Warning Letters (10)
- 2025-07-08
CGMP/Food for Animals/Prepared, Packed or Held Under Insanitary Conditions/Adulterated
J.D. Heiskell Holdings LLC
- 2024-04-16
CGMP/Medicated Feeds/Adulterated
Appleton City Feed Service LLC
- 2024-03-19
CGMP/Medicated Feeds/Adulterated
Furst-McNess Company
- 2024-02-13
CGMP/Hazard Analysis/Risk-Based Preventive Controls for Food for Animals (PCAF)/Adulterated
Battle Creek Co-op/CHS, LLC dba Progressive Nutrition
- 2023-12-12
CGMP/Medicated Feeds/Adulterated
Nutra Blend, LLC subsidiary of Land O’Lakes
- 2023-10-24
CGMP/Medicated Feeds/Adulterated
Suther Feeds, Inc.
- 2022-12-27
CGMP/Medicated Feeds/Adulterated
Land View, Inc.
- 2022-12-20
CGMP/Medicated Feeds/Adulterated
CHS Inc./CHS River Plains
- 2022-11-22
CGMP/Medicated Feeds/Adulterated
Effingham Equity
- 2022-08-02
CGMP/Animal Food/Adulterated
Dairy Feeds, Inc.
See Also (8)
- Guidance for Industry: Foreign Supplier Verification Programs for Importers of Food for Humans and Animals (Status: Final)
- CVM GFI #120 Veterinary Feed Directive Regulation Questions and Answers (Status: Final)
- CVM GFI #61 Special Considerations, Incentives, and Programs to Support the Approval of New Animal Drugs for Minor Uses and for Minor Species (Status: Final)
- CVM GFI #272 Practices to Prevent Unsafe Contamination of Animal Feed from Drug Carryover (Status: Final)
- CVM GFI #245 Hazard Analysis and Risk-Based Preventive Controls for Food for Animals (Status: Final)
- Draft Guidance for Industry: Questions and Answers on the Accredited Third-Party Certification Program (Status: Draft)
- CVM GFI #246 Hazard Analysis and Risk-Based Preventive Controls for Food for Animals: Supply-Chain Program (Status: Draft)
- CVM GFI #235 Current Good Manufacturing Practice Requirements for Food for Animals (Status: Final)