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Guidance on the Content of Premarket Notification [510(K)] Submissions for Piston Syringes

FinalCenter for Devices and Radiological Health03/31/1993

Description

This guidance was written prior to the February 27, 1997 implementation of FDA’s Good Guidance Practices, GGP’s. It does not create or confer rights for or on any person and does not operate to bind FDA or the public. An alternative approach may be used if such approach satisfies the requirements of the applicable statute, regulations, or both. This guidance will be updated in the next revision to include the standard elements of GGP’s.

Scope & Applicability

Product Classes

6
Protective Restraints

Devices including wristlets, anklets, vests, and body holders intended for medical purposes

Protective Restraint

Common name for devices in Class I, Panel 80; The guidance covers premarket notification submissions for protective restraints.; The device type covered by this guidance document

Wheelchair Accessory

Classification regulation revised alongside protective restraints

Protective restraint devices

Considered Tier 2 devices requiring focussed scientific review

Class I

General manual surgical instruments exempt from 510(k)

Class II

The devices that are the subject of this guidance are Class II non-spinal metallic bone screws and washers

Stakeholders

7
Manufacturer

Entity responsible for submitting NDINs

FDA advisory committee

discussed potential liver toxicity of ximelagatran in September 2004

Health Care Workers

Nurses, aides, and technicians who typically use the device.

Licensed healthcare practitioner

Authorized to order prescription devices

Importer

Must comply with registration if meeting facility/responsible person definitions

Distributor

Entity responsible for submitting NDINs

Applicant

Entity submitting development data and knowledge; Entity performing the work process for change

Regulatory Context

Attributes

3
Intended Use

Evidence of a new intended use based on communications

Color Coding

Mechanism to distinguish tools for raw vs RTE areas

Substantial equivalence

Regulatory standard for 510(k) clearance; demonstration required for 510(k) submission; regulatory standard for 510(k) clearance; Comparison of subject device parameters to predicate 510(k) submission numbers.

Identified Hazards

Hazards

5
Flammability

Identified risk to health for surgical masks.

Misapplication

Pictorial and written warnings about misapplication hazards

Protective Restraint Injuries

Prevalence of injuries may vary between institutions.

Incorrect placement

Specific warning required on device labels

Asphyxiation

Injury and death risk associated with protective restraints

Related CFR Sections (5)

Related Warning Letters (10)

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    2025-09-16
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    2025-08-05
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    2025-07-15
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    2025-05-27
  • Investigational Device Exemptions (IDE)/Premarket Approval Application (PMA) Adulterated Device

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    2025-03-25
  • CGMP/QSR/Medical Devices/Adulterated

    Optikem International, Inc.

    2024-09-10
  • Investigational Device Exemptions (IDE)/Premarket Approval Application (PMA) Adulterated Device

    Shenzhen Moyeah Intelligent Life Technology Co.

    2024-08-28
  • Investigational Device Exemptions (IDE)/Premarket Approval Application (PMA) Adulterated Device

    Adventure Innovations LLC

    2024-08-28
  • Investigational Device Exemptions (IDE)/Premarket Approval Application (PMA) Adulterated Device

    Natures Pillows, Inc. and Top Dog Direct, LLC

    2024-08-28
  • Investigational Device Exemptions (IDE)/Premarket Approval Application (PMA) Adulterated Device

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    2024-08-13

See Also (8)