Back to Explorer

Investigational Medical Laser Significant Risk Device (Laser Notice 31)

FinalCenter for Devices and Radiological Health05/18/1981

Description

Thisguideprovides: Criteria for Considering an Investigational Medical Laser Device as a Significant Risk Device

Scope & Applicability

Product Classes

3
Class III Laser Product

Higher power versions may be considered significant risk devices depending on emission and application.

Class IV Laser Product

Laser products generally considered significant risk devices.

Significant Risk Device

Devices requiring full IDE submission

Stakeholders

3
Investigator

Responsible for qualifications, training, and trial conduct; Individual responsible for trial conduct and data governance at a site.; May delegate tasks but retains overall responsibility; Person responsible for the conduct of the clinical trial at a trial site; Responsible for trial conduct and participant safety; Responsible for trial conduct, data integrity, and investigational product management.; Individual responsible for trial conduct at a site and informing the institution.; maintaining

Sponsor

Entity responsible for submitting applications under section 524B

Institutional Review Board

Governs top dose in clinical studies

Regulatory Context

Attributes

1
Substantially Equivalent

Regulatory status for products similar to a predicate

Related CFR Sections (1)

Related Warning Letters (5)

  • Bioresearch Monitoring Program/Institutional Review Board (IRB)

    United Health Products, Inc.

    2025-05-20
  • Bioresearch Monitoring Program/IRB

    Massachusetts Institute of Technology MIT

    2024-07-16
  • Investigational Review Board (IRB)

    Nobles Medical Technology II, Inc.

    2024-03-12
  • CGMP/QSR/Medical Devices/Adulterated

    Synovo Production, Inc.

    2023-04-04
  • Investigational Device Exemptions (Clinical Investigator)

    Kennedy, Philip R.

    2020-04-07

See Also (8)

Investigational Medical Laser Significant Risk Device (Laser Notice 31) | Guideline Explorer | BioRegHub