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Center for Devices and Radiological Health (CDRH) Appeals Processes: Guidance for Industry and Food and Drug Administration Staff

FinalCenter for Devices and Radiological Health03/02/2022

Description

This guidance documentdescribes the processes available to outside stakeholders to request additional review of decisions or actions by Center for Devices and Radiological Health (CDRH or the Center) employees.

Scope & Applicability

Product Classes

3
Combination Product

Products combining drug, device, or biological constituents; Generally recommended for Enhanced Documentation; Requires 14971-based framework incorporating ICH Q9; A drug-device combination where the device constituent part detects ingestion.

Radiation-emitting electronic product

Subject of performance standard review

Innovative device

Devices for vulnerable patient populations

Stakeholders

7
CDRH Ombudsman

Assists in clarifying issues and mediating meetings; Engaged prior to filing a formal request for review or for bias allegations

Dockets Management Staff

Entity responsible for receiving written comments on the guidance.

Commissioner

Decision maker in expedited withdrawal procedures; Provides opportunity for a meeting or written appeal during withdrawal procedures.; FDA Commissioner or their designee presiding over appeals

Subject Matter Experts

External individuals providing advice to the review authority

Special Government Employees

Qualified individuals participating on Advisory Committees

Ombudsman

Official who investigates concerns regarding DRP panel members; Point of contact for special circumstances in appeals

Dispute Resolution Panel

DRP convened for center-level reviews

Regulatory Context

Attributes

1
Significant Decision

Decisions defined under Section 517A subject to specific timelines

Related CFR Sections (7)

See Also (8)